Ussher JR - Search Results

1

Myocardial fatty acid metabolism in health and disease.

Lopaschuk GD, Ussher JR, Folmes CD, Jaswal JS, Stanley WC. Lopaschuk GD, et al. Among authors: ussher jr. Physiol Rev. 2010 Jan;90(1):207-58. doi: 10.1152/physrev.00015.2009. Physiol Rev. 2010. PMID: 20086077 Free article. Review.

2

Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance.

Koves TR, Ussher JR, Noland RC, Slentz D, Mosedale M, Ilkayeva O, Bain J, Stevens R, Dyck JR, Newgard CB, Lopaschuk GD, Muoio DM. Koves TR, et al. Among authors: ussher jr. Cell Metab. 2008 Jan;7(1):45-56. doi: 10.1016/j.cmet.2007.10.013. Cell Metab. 2008. PMID: 18177724 Free article.

3

The malonyl CoA axis as a potential target for treating ischaemic heart disease.

Ussher JR, Lopaschuk GD. Ussher JR, et al. Cardiovasc Res. 2008 Jul 15;79(2):259-68. doi: 10.1093/cvr/cvn130. Epub 2008 May 22. Cardiovasc Res. 2008. PMID: 18499682 Review.

4

Targeting malonyl CoA inhibition of mitochondrial fatty acid uptake as an approach to treat cardiac ischemia/reperfusion.

Ussher JR, Lopaschuk GD. Ussher JR, et al. Basic Res Cardiol. 2009 Mar;104(2):203-10. doi: 10.1007/s00395-009-0003-9. Epub 2009 Feb 26. Basic Res Cardiol. 2009. PMID: 19242641 Review.

5

Insulin-stimulated cardiac glucose oxidation is increased in high-fat diet-induced obese mice lacking malonyl CoA decarboxylase.

Ussher JR, Koves TR, Jaswal JS, Zhang L, Ilkayeva O, Dyck JR, Muoio DM, Lopaschuk GD. Ussher JR, et al. Diabetes. 2009 Aug;58(8):1766-75. doi: 10.2337/db09-0011. Epub 2009 May 28. Diabetes. 2009. PMID: 19478144 Free PMC article.

6

Role of the atypical protein kinase Czeta in regulation of 5'-AMP-activated protein kinase in cardiac and skeletal muscle.

Ussher JR, Jaswal JS, Wagg CS, Armstrong HE, Lopaschuk DG, Keung W, Lopaschuk GD. Ussher JR, et al. Am J Physiol Endocrinol Metab. 2009 Aug;297(2):E349-57. doi: 10.1152/ajpendo.00009.2009. Am J Physiol Endocrinol Metab. 2009. PMID: 19625676 Free article.

7

Type 1 diabetic cardiomyopathy in the Akita (Ins2WT/C96Y) mouse model is characterized by lipotoxicity and diastolic dysfunction with preserved systolic function.

Basu R, Oudit GY, Wang X, Zhang L, Ussher JR, Lopaschuk GD, Kassiri Z. Basu R, et al. Among authors: ussher jr. Am J Physiol Heart Circ Physiol. 2009 Dec;297(6):H2096-108. doi: 10.1152/ajpheart.00452.2009. Epub 2009 Oct 2. Am J Physiol Heart Circ Physiol. 2009. PMID: 19801494 Free article.

8

Targeting intermediary metabolism in the hypothalamus as a mechanism to regulate appetite.

Lopaschuk GD, Ussher JR, Jaswal JS. Lopaschuk GD, et al. Among authors: ussher jr. Pharmacol Rev. 2010 Jun;62(2):237-64. doi: 10.1124/pr.109.002428. Epub 2010 Apr 14. Pharmacol Rev. 2010. PMID: 20392806 Review.

9

Inhibition of de novo ceramide synthesis reverses diet-induced insulin resistance and enhances whole-body oxygen consumption.

Ussher JR, Koves TR, Cadete VJ, Zhang L, Jaswal JS, Swyrd SJ, Lopaschuk DG, Proctor SD, Keung W, Muoio DM, Lopaschuk GD. Ussher JR, et al. Diabetes. 2010 Oct;59(10):2453-64. doi: 10.2337/db09-1293. Epub 2010 Jun 3. Diabetes. 2010. PMID: 20522596 Free PMC article.

10

Cardiac diacylglycerol accumulation in high fat-fed mice is associated with impaired insulin-stimulated glucose oxidation.

Zhang L, Ussher JR, Oka T, Cadete VJ, Wagg C, Lopaschuk GD. Zhang L, et al. Among authors: ussher jr. Cardiovasc Res. 2011 Jan 1;89(1):148-56. doi: 10.1093/cvr/cvq266. Epub 2010 Aug 20. Cardiovasc Res. 2011. PMID: 20729341

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