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Dar HH, Mikulska-Ruminska K, Tyurina YY, Luci DK, Yasgar A, Samovich SN, Kapralov AA, Souryavong AB, Tyurin VA, Amoscato AA, Epperly MW, Shurin GV, Standley M, Holman TR, St Croix CM, Watkins SC, VanDemark AP, Rana S, Zakharov AV, Simeonov A, Marugan J, Mallampalli RK, Wenzel SE, Greenberger JS, Rai G, Bayir H, Bahar I, Kagan VE. Discovering selective antiferroptotic inhibitors of the 15LOX/PEBP1 complex noninterfering with biosynthesis of lipid mediators. Proc Natl Acad Sci U S A. 2023 Jun 20;120(25):e2218896120. doi: 10.1073/pnas.2218896120. Epub 2023 Jun 16. PubMed PMID: 37327313; PubMed Central PMCID: PMC10288584.
Wang W, Wong NK, Bok SL, Xu Y, Guo Y, Xu L, Zuo M, St Croix CM, Mao G, Kapralov A, Bayir H, Kagan VE, Yang D. Visualizing Cardiolipin In Situ with HKCL-1M, a Highly Selective and Sensitive Fluorescent Probe. J Am Chem Soc. 2023 May 24;145(20):11311-11322. doi: 10.1021/jacs.3c00243. Epub 2023 Apr 27. PubMed PMID: 37103240; PubMed Central PMCID: PMC10214440.
Undamatla R, Fagunloye OG, Chen J, Edmunds LR, Murali A, Mills A, Xie B, Pangburn MM, Sipula I, Gibson G, St Croix C, Jurczak MJ. Reduced mitophagy is an early feature of NAFLD and liver-specific PARKIN knockout hastens the onset of steatosis, inflammation and fibrosis. Sci Rep. 2023 May 10;13(1):7575. doi: 10.1038/s41598-023-34710-x. PubMed PMID: 37165006; PubMed Central PMCID: PMC10172344.
Henpita C, Vyas R, Healy CL, Kieu TL, Gurkar AU, Yousefzadeh MJ, Cui Y, Lu A, Angelini LA, O'Kelly RD, McGowan SJ, Chandrasekhar S, Vanderpool RR, Hennessy-Wack D, Ross MA, Bachman TN, McTiernan C, Pillai SPS, Ladiges W, Lavasani M, Huard J, Beer-Stolz D, St Croix CM, Watkins SC, Robbins PD, Mora AL, Kelley EE, Wang Y, O'Connell TD, Niedernhofer LJ. Loss of DNA repair mechanisms in cardiac myocytes induce dilated cardiomyopathy. Aging Cell. 2023 Apr;22(4):e13782. doi: 10.1111/acel.13782. Epub 2023 Feb 3. PubMed PMID: 36734200; PubMed Central PMCID: PMC10086531.
Gupta U, Ghosh S, Wallace CT, Shang P, Xin Y, Nair AP, Yazdankhah M, Strizhakova A, Ross MA, Liu H, Hose S, Stepicheva NA, Chowdhury O, Nemani M, Maddipatla V, Grebe R, Das M, Lathrop KL, Sahel JA, Zigler JS Jr, Qian J, Ghosh A, Sergeev Y, Handa JT, St Croix CM, Sinha D. Increased LCN2 (lipocalin 2) in the RPE decreases autophagy and activates inflammasome-ferroptosis processes in a mouse model of dry AMD. Autophagy. 2023 Jan;19(1):92-111. doi: 10.1080/15548627.2022.2062887. Epub 2022 Apr 26. PubMed PMID: 35473441; PubMed Central PMCID: PMC9809950.
Oghifobibi OA, Toader AE, Nicholas MA, Nelson BP, Alindogan NG, Wolf MS, Kline AE, Nouraie SM, Bondi CO, Iordanova B, Clark RS, Bayır H, Loughran PA, Watkins SC, St Croix CM, Kochanek PM, Vazquez AL, Manole MD. Resuscitation with epinephrine worsens cerebral capillary no-reflow after experimental pediatric cardiac arrest: An in vivo multiphoton microscopy evaluation. J Cereb Blood Flow Metab. 2022 Dec;42(12):2255-2269. doi: 10.1177/0271678X221113022. Epub 2022 Jul 19. PubMed PMID: 35854408; PubMed Central PMCID: PMC9670003.
Loughran PA, Ross MA, St Croix CM. Immunohistochemistry. Curr Protoc. 2022 Sep;2(9):e549. doi: 10.1002/cpz1.549. PubMed PMID: 36102926.
Jacobs JL, Bain W, Naqvi A, Staines B, Castanha PMS, Yang H, Boltz VF, Barratt-Boyes S, Marques ETA, Mitchell SL, Methé B, Olonisakin TF, Haidar G, Burke TW, Petzold E, Denny T, Woods CW, McVerry BJ, Lee JS, Watkins SC, St Croix CM, Morris A, Kearney MF, Ladinsky MS, Bjorkman PJ, Kitsios GD, Mellors JW. Severe Acute Respiratory Syndrome Coronavirus 2 Viremia Is Associated With Coronavirus Disease 2019 Severity and Predicts Clinical Outcomes. Clin Infect Dis. 2022 May 3;74(9):1525-1533. doi: 10.1093/cid/ciab686. PubMed PMID: 34374761; PubMed Central PMCID: PMC9070832.
Lamade AM, Wu L, Dar HH, Mentrup HL, Shrivastava IH, Epperly MW, St Croix CM, Tyurina YY, Anthonymuthu TS, Yang Q, Kapralov AA, Huang Z, Mao G, Amoscato AA, Hier ZE, Artyukhova MA, Shurin G, Rosenbaum JC, Gough PJ, Bertin J, VanDemark AP, Watkins SC, Mollen KP, Bahar I, Greenberger JS, Kagan VE, Whalen MJ, Bayır H. Inactivation of RIP3 kinase sensitizes to 15LOX/PEBP1-mediated ferroptotic death. Redox Biol. 2022 Apr;50:102232. doi: 10.1016/j.redox.2022.102232. Epub 2022 Jan 10. PubMed PMID: 35101798; PubMed Central PMCID: PMC8804265.
Koudelka A, Cechova V, Rojas M, Mitash N, Bondonese A, St Croix C, Ross MA, Freeman BA. Fatty acid nitroalkene reversal of established lung fibrosis. Redox Biol. 2022 Apr;50:102226. doi: 10.1016/j.redox.2021.102226. Epub 2021 Dec 29. PubMed PMID: 35150970; PubMed Central PMCID: PMC8844680.
Kajiwara K, Beharier O, Chng CP, Goff JP, Ouyang Y, St Croix CM, Huang C, Kagan VE, Hsia KJ, Sadovsky Y. Ferroptosis induces membrane blebbing in placental trophoblasts. J Cell Sci. 2022 Mar 1;135(5). doi: 10.1242/jcs.255737. Epub 2021 Apr 20. PubMed PMID: 33414166; PubMed Central PMCID: PMC8084576.
Jin M, Watkins S, Larriba Y, Wallace C, Croix CS, Zhou X, Zhao J, Peddada S, Wenzel SE. Reply. J Allergy Clin Immunol. 2022 Mar;149(3):1132-1133. doi: 10.1016/j.jaci.2021.12.763. Epub 2022 Jan 6. PubMed PMID: 35000771.
Heiman P, Mohsen AW, Karunanidhi A, St Croix C, Watkins S, Koppes E, Haas R, Vockley J, Ghaloul-Gonzalez L. Mitochondrial dysfunction associated with TANGO2 deficiency. Sci Rep. 2022 Feb 23;12(1):3045. doi: 10.1038/s41598-022-07076-9. PubMed PMID: 35197517; PubMed Central PMCID: PMC8866466.
Dar HH, Epperly MW, Tyurin VA, Amoscato AA, Anthonymuthu TS, Souryavong AB, Kapralov AA, Shurin GV, Samovich SN, St Croix CM, Watkins SC, Wenzel SE, Mallampalli RK, Greenberger JS, Bayır H, Kagan VE, Tyurina YY. P. aeruginosa augments irradiation injury via 15-lipoxygenase-catalyzed generation of 15-HpETE-PE and induction of theft-ferroptosis. JCI Insight. 2022 Feb 22;7(4). doi: 10.1172/jci.insight.156013. PubMed PMID: 35041620; PubMed Central PMCID: PMC8876480.
Jin M, Watkins S, Larriba Y, Wallace C, St Croix C, Zhou X, Zhao J, Peddada S, Wenzel SE. Real-time imaging of asthmatic epithelial cells identifies migratory deficiencies under type-2 conditions. J Allergy Clin Immunol. 2022 Feb;149(2):579-588. doi: 10.1016/j.jaci.2021.08.027. Epub 2021 Sep 20. PubMed PMID: 34547368; PubMed Central PMCID: PMC8821171.
Yuan S, Hahn SA, Miller MP, Sanker S, Calderon MJ, Sullivan M, Dosunmu-Ogunbi AM, Fazzari M, Li Y, Reynolds M, Wood KC, St Croix CM, Stolz D, Cifuentes-Pagano E, Navas P, Shiva S, Schopfer FJ, Pagano PJ, Straub AC. Cooperation between CYB5R3 and NOX4 via coenzyme Q mitigates endothelial inflammation. Redox Biol. 2021 Nov;47:102166. doi: 10.1016/j.redox.2021.102166. Epub 2021 Oct 14. PubMed PMID: 34656824; PubMed Central PMCID: PMC8577475.
Kowalczyk A, Gbadamosi O, Kolor K, Sosa J, Andrzejczuk L, Gibson G, St Croix C, Chikina M, Aizenman E, Clark N, Kiselyov K. Evolutionary rate covariation identifies SLC30A9 (ZnT9) as a mitochondrial zinc transporter. Biochem J. 2021 Sep 17;478(17):3205-3220. doi: 10.1042/BCJ20210342. PubMed PMID: 34397090; PubMed Central PMCID: PMC10491466.
Marrocco A, Frawley K, Pearce LL, Peterson J, O'Brien JP, Mullett SJ, Wendell SG, St Croix CM, Mischler SE, Ortiz LA. Metabolic Adaptation of Macrophages as Mechanism of Defense against Crystalline Silica. J Immunol. 2021 Sep 15;207(6):1627-1640. doi: 10.4049/jimmunol.2000628. Epub 2021 Aug 25. PubMed PMID: 34433619; PubMed Central PMCID: PMC8428747.
Jang S, Chapa-Dubocq XR, Tyurina YY, St Croix CM, Kapralov AA, Tyurin VA, Bayır H, Kagan VE, Javadov S. Elucidating the contribution of mitochondrial glutathione to ferroptosis in cardiomyocytes. Redox Biol. 2021 Sep;45:102021. doi: 10.1016/j.redox.2021.102021. Epub 2021 Jun 1. PubMed PMID: 34102574; PubMed Central PMCID: PMC8187237.
Missinato MA, Zuppo DA, Watkins SC, Bruchez MP, Tsang M. Zebrafish heart regenerates after chemoptogenetic cardiomyocyte depletion. Dev Dyn. 2021 Jul;250(7):986-1000. doi: 10.1002/dvdy.305. Epub 2021 Feb 8. PubMed PMID: 33501711; PubMed Central PMCID: PMC8249307.
Chen D, Gregory AD, Li X, Wei J, Burton CL, Gibson G, Scott SJ, St Croix CM, Zhang Y, Shapiro SD. RIP3-dependent necroptosis contributes to the pathogenesis of chronic obstructive pulmonary disease. JCI Insight. 2021 Jun 22;6(12). doi: 10.1172/jci.insight.144689. PubMed PMID: 34156033; PubMed Central PMCID: PMC8262480.
Sharifi-Sanjani M, Berman M, Goncharov D, Alhamaydeh M, Avolio TG, Baust J, Chang B, Kobir A, Ross M, St Croix C, Nouraie SM, McTiernan CF, Moravec CS, Goncharova E, Al Ghouleh I. Yes-Associated Protein (Yap) Is Up-Regulated in Heart Failure and Promotes Cardiac Fibroblast Proliferation. Int J Mol Sci. 2021 Jun 7;22(11). doi: 10.3390/ijms22116164. PubMed PMID: 34200497; PubMed Central PMCID: PMC8201133.
Liu Y, Lear T, Larsen M, Lin B, Cao Q, Alfaras I, Kennerdell J, Salminen L, Camarco D, Lockwood K, Ma J, Liu J, Tan J, Myerburg M, Chen Y, St Croix C, Sekine Y, Evankovich J, Finkel T, Chen B. Modulation of lysosomal function as a therapeutic approach for coronaviral infections. Res Sq. 2021 Apr 23;. doi: 10.21203/rs.3.rs-419305/v1. PubMed PMID: 34013250; PubMed Central PMCID: PMC8132244.
Bain WG, Peñaloza HF, Ladinsky MS, van der Geest R, Sullivan M, Ross M, Kitsios GD, Methé BA, McVerry BJ, Morris A, Watson AM, Watkins SC, St Croix CM, Stolz DB, Bjorkman PJ, Lee JS. Lower Respiratory Tract Myeloid Cells Harbor SARS-Cov-2 and Display an Inflammatory Phenotype. Chest. 2021 Mar;159(3):963-966. doi: 10.1016/j.chest.2020.10.083. Epub 2020 Nov 18. PubMed PMID: 33217417; PubMed Central PMCID: PMC7671922.
Olonisakin TF, Suber T, Gonzalez-Ferrer S, Xiong Z, Peñaloza HF, van der Geest R, Xiong Y, Osei-Hwedieh DO, Tejero J, Rosengart MR, Mars WM, Van Tyne D, Perlegas A, Brashears S, Kim-Shapiro DB, Gladwin MT, Bachman MA, Hod EA, St Croix C, Tyurina YY, Kagan VE, Mallampalli RK, Ray A, Ray P, Lee JS. Stressed erythrophagocytosis induces immunosuppression during sepsis through heme-mediated STAT1 dysregulation. J Clin Invest. 2021 Jan 4;131(1). doi: 10.1172/JCI137468. PubMed PMID: 32941182; PubMed Central PMCID: PMC7773401.
Beharier O, Tyurin VA, Goff JP, Guerrero-Santoro J, Kajiwara K, Chu T, Tyurina YY, St Croix CM, Wallace CT, Parry S, Parks WT, Kagan VE, Sadovsky Y. PLA2G6 guards placental trophoblasts against ferroptotic injury. Proc Natl Acad Sci U S A. 2020 Nov 3;117(44):27319-27328. doi: 10.1073/pnas.2009201117. Epub 2020 Oct 21. PubMed PMID: 33087576; PubMed Central PMCID: PMC7959495.
Pham D, Deter CJ, Reinard MC, Gibson GA, Kiselyov K, Yu W, Sandulache VC, St Croix CM, Koide K. Using Ligand-Accelerated Catalysis to Repurpose Fluorogenic Reactions for Platinum or Copper. ACS Cent Sci. 2020 Oct 28;6(10):1772-1788. doi: 10.1021/acscentsci.0c00676. Epub 2020 Sep 18. PubMed PMID: 33145414; PubMed Central PMCID: PMC7596870.
Van Laar VS, Chen J, Zharikov AD, Bai Q, Di Maio R, Dukes AA, Hastings TG, Watkins SC, Greenamyre JT, St Croix CM, Burton EA. α-Synuclein amplifies cytoplasmic peroxide flux and oxidative stress provoked by mitochondrial inhibitors in CNS dopaminergic neurons in vivo. Redox Biol. 2020 Oct;37:101695. doi: 10.1016/j.redox.2020.101695. Epub 2020 Aug 22. PubMed PMID: 32905883; PubMed Central PMCID: PMC7486459.
Pham D, Basu U, Pohorilets I, St Croix CM, Watkins SC, Koide K. Fluorogenic Probe Using a Mislow-Evans Rearrangement for Real-Time Imaging of Hydrogen Peroxide. Angew Chem Int Ed Engl. 2020 Sep 28;59(40):17435-17441. doi: 10.1002/anie.202007104. Epub 2020 Aug 6. PubMed PMID: 32585075.
Carpenter MA, Wang Y, Telmer CA, Schmidt BF, Yang Z, Bruchez MP. Protein Proximity Observed Using Fluorogen Activating Protein and Dye Activated by Proximal Anchoring (FAP-DAPA) System. ACS Chem Biol. 2020 Sep 18;15(9):2433-2443. doi: 10.1021/acschembio.0c00419. Epub 2020 Aug 17. PubMed PMID: 32786268; PubMed Central PMCID: PMC8796707.
Bain W, Penaloza HF, Ladinsky MS, van der Geest R, Sullivan M, Ross M, Kitsios GD, Methe B, McVerry BJ, Morris A, Watson AM, Watkins SC, St Croix CM, Stolz DB, Bjorkman PJ, Lee JS. Lower respiratory tract myeloid cells harbor SARS-CoV-2 and display an inflammatory phenotype. medRxiv. 2020 Aug 14;. doi: 10.1101/2020.08.11.20171967. PubMed PMID: 32817968; PubMed Central PMCID: PMC7430612.
Li X, Kim SE, Chen TY, Wang J, Yang X, Tabib T, Tan J, Guo B, Fung S, Zhao J, Sembrat J, Rojas M, Shiva S, Lafyatis R, St Croix C, Alder JK, Di YP, Kass DJ, Zhang Y. Toll interacting protein protects bronchial epithelial cells from bleomycin-induced apoptosis. FASEB J. 2020 Aug;34(8):9884-9898. doi: 10.1096/fj.201902636RR. Epub 2020 Jun 28. PubMed PMID: 32596871; PubMed Central PMCID: PMC8175118.
Das S, St Croix C, Good M, Chen J, Zhao J, Hu S, Ross M, Myerburg MM, Pilewski JM, Williams J, Wenzel SE, Kolls JK, Ray A, Ray P. Interleukin-22 Inhibits Respiratory Syncytial Virus Production by Blocking Virus-Mediated Subversion of Cellular Autophagy. iScience. 2020 Jul 24;23(7):101256. doi: 10.1016/j.isci.2020.101256. Epub 2020 Jun 10. PubMed PMID: 32580124; PubMed Central PMCID: PMC7317237.
Vasamsetti SB, Coppin E, Zhang X, Florentin J, Koul S, Götberg M, Clugston AS, Thoma F, Sembrat J, Bullock GC, Kostka D, St Croix CM, Chattopadhyay A, Rojas M, Mulukutla SR, Dutta P. Apoptosis of hematopoietic progenitor-derived adipose tissue-resident macrophages contributes to insulin resistance after myocardial infarction. Sci Transl Med. 2020 Jul 22;12(553). doi: 10.1126/scitranslmed.aaw0638. PubMed PMID: 32718989; PubMed Central PMCID: PMC7813555.
Zhao J, Dar HH, Deng Y, St Croix CM, Li Z, Minami Y, Shrivastava IH, Tyurina YY, Etling E, Rosenbaum JC, Nagasaki T, Trudeau JB, Watkins SC, Bahar I, Bayır H, VanDemark AP, Kagan VE, Wenzel SE. PEBP1 acts as a rheostat between prosurvival autophagy and ferroptotic death in asthmatic epithelial cells. Proc Natl Acad Sci U S A. 2020 Jun 23;117(25):14376-14385. doi: 10.1073/pnas.1921618117. Epub 2020 Jun 8. PubMed PMID: 32513718; PubMed Central PMCID: PMC7321965.
Googins MR, Woghiren-Afegbua AO, Calderon M, St Croix CM, Kiselyov KI, VanDemark AP. Structural and functional divergence of GDAP1 from the glutathione S-transferase superfamily. FASEB J. 2020 May;34(5):7192-7207. doi: 10.1096/fj.202000110R. Epub 2020 Apr 10. PubMed PMID: 32274853; PubMed Central PMCID: PMC9394736.
Perkins LA, Bruchez MP. Fluorogen activating protein toolset for protein trafficking measurements. Traffic. 2020 Apr;21(4):333-348. doi: 10.1111/tra.12722. Epub 2020 Mar 1. Review. PubMed PMID: 32080949; PubMed Central PMCID: PMC7462100.
Xie W, Jiao B, Bai Q, Ilin VA, Sun M, Burton CE, Kolodieznyi D, Calderon MJ, Stolz DB, Opresko PL, St Croix CM, Watkins S, Van Houten B, Bruchez MP, Burton EA. Chemoptogenetic ablation of neuronal mitochondria in vivo with spatiotemporal precision and controllable severity. Elife. 2020 Mar 17;9. doi: 10.7554/eLife.51845. PubMed PMID: 32180546; PubMed Central PMCID: PMC7077989.
Kapralov AA, Yang Q, Dar HH, Tyurina YY, Anthonymuthu TS, Kim R, St Croix CM, Mikulska-Ruminska K, Liu B, Shrivastava IH, Tyurin VA, Ting HC, Wu YL, Gao Y, Shurin GV, Artyukhova MA, Ponomareva LA, Timashev PS, Domingues RM, Stoyanovsky DA, Greenberger JS, Mallampalli RK, Bahar I, Gabrilovich DI, Bayır H, Kagan VE. Redox lipid reprogramming commands susceptibility of macrophages and microglia to ferroptotic death. Nat Chem Biol. 2020 Mar;16(3):278-290. doi: 10.1038/s41589-019-0462-8. Epub 2020 Feb 17. PubMed PMID: 32080625; PubMed Central PMCID: PMC7233108.
Jobbagy S, Vitturi DA, Salvatore SR, Pires MF, Rowart P, Emlet DR, Ross M, Hahn S, St Croix C, Wendell SG, Subramanya AR, Straub AC, Tan RJ, Schopfer FJ. Nrf2 activation protects against lithium-induced nephrogenic diabetes insipidus. JCI Insight. 2020 Jan 16;5(1). doi: 10.1172/jci.insight.128578. PubMed PMID: 31941842; PubMed Central PMCID: PMC7030822.
Wang Y, Palmfeldt J, Gregersen N, Makhov AM, Conway JF, Wang M, McCalley SP, Basu S, Alharbi H, St Croix C, Calderon MJ, Watkins S, Vockley J. Mitochondrial fatty acid oxidation and the electron transport chain comprise a multifunctional mitochondrial protein complex. J Biol Chem. 2019 Aug 16;294(33):12380-12391. doi: 10.1074/jbc.RA119.008680. Epub 2019 Jun 24. PubMed PMID: 31235473; PubMed Central PMCID: PMC6699831.
Jang S, Kumar N, Beckwitt EC, Kong M, Fouquerel E, Rapić-Otrin V, Prasad R, Watkins SC, Khuu C, Majumdar C, David SS, Wilson SH, Bruchez MP, Opresko PL, Van Houten B. Damage sensor role of UV-DDB during base excision repair. Nat Struct Mol Biol. 2019 Aug;26(8):695-703. doi: 10.1038/s41594-019-0261-7. Epub 2019 Jul 22. PubMed PMID: 31332353; PubMed Central PMCID: PMC6684372.
Sehrawat A, Samanta SK, Hahm ER, St Croix C, Watkins S, Singh SV. Withaferin A-mediated apoptosis in breast cancer cells is associated with alterations in mitochondrial dynamics. Mitochondrion. 2019 Jul;47:282-293. doi: 10.1016/j.mito.2019.01.003. Epub 2019 Jan 24. PubMed PMID: 30685490; PubMed Central PMCID: PMC6599725.
Tyurina YY, St Croix CM, Watkins SC, Watson AM, Epperly MW, Anthonymuthu TS, Kisin ER, Vlasova II, Krysko O, Krysko DV, Kapralov AA, Dar HH, Tyurin VA, Amoscato AA, Popova EN, Bolevich SB, Timashev PS, Kellum JA, Wenzel SE, Mallampalli RK, Greenberger JS, Bayir H, Shvedova AA, Kagan VE. Redox (phospho)lipidomics of signaling in inflammation and programmed cell death. J Leukoc Biol. 2019 Jul;106(1):57-81. doi: 10.1002/JLB.3MIR0119-004RR. Epub 2019 May 9. Review. PubMed PMID: 31071242; PubMed Central PMCID: PMC6626990.
Novelli EM, Little-Ihrig L, Knupp HE, Rogers NM, Yao M, Baust JJ, Meijles D, St Croix CM, Ross MA, Pagano PJ, DeVallance ER, Miles G, Potoka KP, Isenberg JS, Gladwin MT. Vascular TSP1-CD47 signaling promotes sickle cell-associated arterial vasculopathy and pulmonary hypertension in mice. Am J Physiol Lung Cell Mol Physiol. 2019 Jun 1;316(6):L1150-L1164. doi: 10.1152/ajplung.00302.2018. Epub 2019 Mar 20. PubMed PMID: 30892078; PubMed Central PMCID: PMC6620668.
Patil P, Falabella M, Saeed A, Lee D, Kaufman B, Shiva S, Croix CS, Van Houten B, Niedernhofer LJ, Robbins PD, Lee J, Gwendolyn S, Vo NV. Oxidative stress-induced senescence markedly increases disc cell bioenergetics. Mech Ageing Dev. 2019 Jun;180:97-106. doi: 10.1016/j.mad.2019.04.006. Epub 2019 Apr 17. PubMed PMID: 31002926.
Braganza A, Quesnelle K, Bickta J, Reyes C, Wang Y, Jessup M, St Croix C, Arlotti J, Singh SV, Shiva S. Myoglobin induces mitochondrial fusion, thereby inhibiting breast cancer cell proliferation. J Biol Chem. 2019 May 3;294(18):7269-7282. doi: 10.1074/jbc.RA118.006673. Epub 2019 Mar 14. PubMed PMID: 30872402; PubMed Central PMCID: PMC6509513.
Li L, Poloyac SM, Watkins SC, St Croix CM, Alexander H, Gibson GA, Loughran PA, Kirisci L, Clark RS, Kochanek PM, Vazquez AL, Manole MD. Cerebral microcirculatory alterations and the no-reflow phenomenon in vivo after experimental pediatric cardiac arrest. J Cereb Blood Flow Metab. 2019 May;39(5):913-925. doi: 10.1177/0271678X17744717. Epub 2017 Dec 1. PubMed PMID: 29192562; PubMed Central PMCID: PMC6501505.
Falabella M, Kolesar JE, Wallace C, de Jesus D, Sun L, Taguchi YV, Wang C, Wang T, Xiang IM, Alder JK, Maheshan R, Horne W, Turek-Herman J, Pagano PJ, St Croix CM, Sondheimer N, Yatsunyk LA, Johnson FB, Kaufman BA. G-quadruplex dynamics contribute to regulation of mitochondrial gene expression. Sci Rep. 2019 Apr 3;9(1):5605. doi: 10.1038/s41598-019-41464-y. PubMed PMID: 30944353; PubMed Central PMCID: PMC6447596.
Li Y, Cifuentes-Pagano E, DeVallance ER, de Jesus DS, Sahoo S, Meijles DN, Koes D, Camacho CJ, Ross M, St Croix C, Pagano PJ. NADPH oxidase 2 inhibitors CPP11G and CPP11H attenuate endothelial cell inflammation & vessel dysfunction and restore mouse hind-limb flow. Redox Biol. 2019 Apr;22:101143. doi: 10.1016/j.redox.2019.101143. Epub 2019 Feb 15. PubMed PMID: 30897521; PubMed Central PMCID: PMC6435978.
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