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Rapid Generation of Multiple Loci-Engineered Marker-Free Vaccinia Viruses and In Vitro Characterization of Clinical-Grade Oncolytic Poxvirus vvDD-A34R-hCCL5. Molecular therapy. Methods & clinical development. . NIHMSID: NIHMS914502.
Chemokine-targeting, loco-regional chemo-immunotherapy combination for recurrent, platinum-sensitive ovarian cancer induces CXCR3 ligands and markers of type 1 immunity. Clinical cancer research : an official journal of the American Association for Cancer Research. . NIHMSID: NIHMS1767772.
mTOR inhibition suppresses Myc-driven polyposis by inducing immunogenic cell death. Oncogene. . NIHMSID: NIHMS1898476.
ATRX guards against aberrant differentiation in mesenchymal progenitor cells. Nucleic acids research. . NIHMSID: NIHMS1980355.
Gott VL, Gillinov AM, Pyeritz RE, Cameron DE, Reitz BA, Greene PS, Stone CD, Ferris RL, Alejo DE, McKusick VA. Aortic root replacement. Risk factor analysis of a seventeen-year experience with 270 patients. J Thorac Cardiovasc Surg. 1995 Mar;109(3):536-44; discussion 544-5. doi: 10.1016/S0022-5223(95)70286-5. PubMed PMID: 7877316.
Ferris RL, Buck C, Hammond SA, Woods AS, Cotter RJ, Takiguchi M, Igarashi Y, Ichikawa Y, Siliciano RF. Class I-restricted presentation of an HIV-1 gp41 epitope containing an N-linked glycosylation site. Implications for the mechanism of processing of viral envelope proteins. J Immunol. 1996 Jan 15;156(2):834-40. PubMed PMID: 8543840.
Ferris RL, Eisele DW, Tunkel DE. Functional laryngeal dyskinesia in children and adults. Laryngoscope. 1998 Oct;108(10):1520-3. doi: 10.1097/00005537-199810000-00017. PubMed PMID: 9778293.
Ferris RL, Hall C, Sipsas NV, Safrit JT, Trocha A, Koup RA, Johnson RP, Siliciano RF. Processing of HIV-1 envelope glycoprotein for class I-restricted recognition: dependence on TAP1/2 and mechanisms for cytosolic localization. J Immunol. 1999 Feb 1;162(3):1324-32. PubMed PMID: 9973386.
Toung T, Reilly PM, Fuh KC, Ferris R, Bulkley GB. Mesenteric vasoconstriction in response to hemorrhagic shock. Shock. 2000;13(4):267-73. doi: 10.1097/00024382-200004000-00003. PubMed PMID: 10774614.
Hoffmann TK, Müller-Berghaus J, Ferris RL, Johnson JT, Storkus WJ, Whiteside TL. Alterations in the frequency of dendritic cell subsets in the peripheral circulation of patients with squamous cell carcinomas of the head and neck. Clin Cancer Res. 2002 Jun;8(6):1787-93. PubMed PMID: 12060618.
Ferris RL, Koch WM. Connective tissue disease coincident with nasopharyngeal carcinoma: two sporadic cases in a Western population. Arch Otolaryngol Head Neck Surg. 2003 Jan;129(1):101-5. doi: 10.1001/archotol.129.1.101. PubMed PMID: 12525203.
Ferris RL, Kittur DS, Wilasrusmee C, Shah G, Krause E, Ratner L. Early hemodynamic changes after renal transplantation: determinants of low central venous pressure in the recipients and correlation with acute renal dysfunction. Med Sci Monit. 2003 Feb;9(2):CR61-6. PubMed PMID: 12601288.
Ferris RL, Eisele DW. Steroid psychosis after head and neck surgery: case report and review of the literature. Otolaryngol Head Neck Surg. 2003 Nov;129(5):591-2. doi: 10.1016/s0194-5998(03)00717-4. Review. PubMed PMID: 14595285.
Nayak JV, Cook JR, Molina JT, Branch MP, Branstetter BF 4th, Ferris RL, Myers EN. Primary lymphoma of the larynx: new diagnostic and therapeutic approaches. ORL J Otorhinolaryngol Relat Spec. 2003 Nov-Dec;65(6):321-6. doi: 10.1159/000076049. PubMed PMID: 14981324.
Cosetti MK, Smith JC, Branstetter BF, Ferris RL. Radiology quiz case. Ectopic thyroid tissue. Arch Otolaryngol Head Neck Surg. 2004 Jan;130(1):117-9. doi: 10.1001/archotol.130.1.117. PubMed PMID: 14732781.
Ferris RL. Progress in head and neck cancer immunotherapy: can tolerance and immune suppression be reversed?. ORL J Otorhinolaryngol Relat Spec. 2004;66(6):332-40. doi: 10.1159/000081891. Review. PubMed PMID: 15668533.
Wang J, Xi L, Hunt JL, Gooding W, Whiteside TL, Chen Z, Godfrey TE, Ferris RL. Expression pattern of chemokine receptor 6 (CCR6) and CCR7 in squamous cell carcinoma of the head and neck identifies a novel metastatic phenotype. Cancer Res. 2004 Mar 1;64(5):1861-6. doi: 10.1158/0008-5472.can-03-2968. PubMed PMID: 14996750.
Kuss I, Hathaway B, Ferris RL, Gooding W, Whiteside TL. Decreased absolute counts of T lymphocyte subsets and their relation to disease in squamous cell carcinoma of the head and neck. Clin Cancer Res. 2004 Jun 1;10(11):3755-62. doi: 10.1158/1078-0432.CCR-04-0054. PubMed PMID: 15173082.
Sirianni N, Ha PK, Oelke M, Califano J, Gooding W, Westra W, Whiteside TL, Koch WM, Schneck JP, DeLeo A, Ferris RL. Effect of human papillomavirus-16 infection on CD8+ T-cell recognition of a wild-type sequence p53264-272 peptide in patients with squamous cell carcinoma of the head and neck. Clin Cancer Res. 2004 Oct 15;10(20):6929-37. doi: 10.1158/1078-0432.CCR-04-0672. PubMed PMID: 15501971.
Duvvuri U, Simental AA Jr, D'Angelo G, Johnson JT, Ferris RL, Gooding W, Myers EN. Elective neck dissection and survival in patients with squamous cell carcinoma of the oral cavity and oropharynx. Laryngoscope. 2004 Dec;114(12):2228-34. doi: 10.1097/01.mlg.0000149464.73080.20. PubMed PMID: 15564851.
Peng H, Ferris RL, Matthews T, Hiel H, Lopez-Albaitero A, Lustig LR. Characterization of the human nicotinic acetylcholine receptor subunit alpha (alpha) 9 (CHRNA9) and alpha (alpha) 10 (CHRNA10) in lymphocytes. Life Sci. 2004 Dec 3;76(3):263-80. doi: 10.1016/j.lfs.2004.05.031. PubMed PMID: 15531379.
Zhang X, Hunt JL, Landsittel DP, Muller S, Adler-Storthz K, Ferris RL, Shin DM, Chen ZG. Correlation of protease-activated receptor-1 with differentiation markers in squamous cell carcinoma of the head and neck and its implication in lymph node metastasis. Clin Cancer Res. 2004 Dec 15;10(24):8451-9. doi: 10.1158/1078-0432.CCR-04-0546. PubMed PMID: 15625067.
Ferris RL, Hunt JL, Ferrone S. Human leukocyte antigen (HLA) class I defects in head and neck cancer: molecular mechanisms and clinical significance. Immunol Res. 2005;33(2):113-33. doi: 10.1385/IR:33:2:113. Review. PubMed PMID: 16234579.
Hathaway B, Landsittel DP, Gooding W, Whiteside TL, Grandis JR, Siegfried JM, Bigbee WL, Ferris RL. Multiplexed analysis of serum cytokines as biomarkers in squamous cell carcinoma of the head and neck patients. Laryngoscope. 2005 Mar;115(3):522-7. doi: 10.1097/01.mlg.0000157850.16649.b8. PubMed PMID: 15744170.
Ferris RL, Martinez I, Sirianni N, Wang J, López-Albaitero A, Gollin SM, Johnson JT, Khan S. Human papillomavirus-16 associated squamous cell carcinoma of the head and neck (SCCHN): a natural disease model provides insights into viral carcinogenesis. Eur J Cancer. 2005 Mar;41(5):807-15. doi: 10.1016/j.ejca.2004.11.023. PubMed PMID: 15763658.
Ferris RL, Xi L, Raja S, Hunt JL, Wang J, Gooding WE, Kelly L, Ching J, Luketich JD, Godfrey TE. Molecular staging of cervical lymph nodes in squamous cell carcinoma of the head and neck. Cancer Res. 2005 Mar 15;65(6):2147-56. doi: 10.1158/0008-5472.CAN-04-3717. PubMed PMID: 15781625.
Sirianni N, Wang J, Ferris RL. Antiviral activity of Cidofovir on a naturally human papillomavirus-16 infected squamous cell carcinoma of the head and neck (SCCHN) cell line improves radiation sensitivity. Oral Oncol. 2005 Apr;41(4):423-8. doi: 10.1016/j.oraloncology.2004.11.003. PubMed PMID: 15792615.
Shurin GV, Ferris RL, Tourkova IL, Perez L, Lokshin A, Balkir L, Collins B, Chatta GS, Shurin MR. Loss of new chemokine CXCL14 in tumor tissue is associated with low infiltration by dendritic cells (DC), while restoration of human CXCL14 expression in tumor cells causes attraction of DC both in vitro and in vivo. J Immunol. 2005 May 1;174(9):5490-8. doi: 10.4049/jimmunol.174.9.5490. PubMed PMID: 15843547.
Lai SY, Childs EE, Xi S, Coppelli FM, Gooding WE, Wells A, Ferris RL, Grandis JR. Erythropoietin-mediated activation of JAK-STAT signaling contributes to cellular invasion in head and neck squamous cell carcinoma. Oncogene. 2005 Jun 23;24(27):4442-9. doi: 10.1038/sj.onc.1208635. PubMed PMID: 15856028.
Kuss I, Schaefer C, Godfrey TE, Ferris RL, Harris JM, Gooding W, Whiteside TL. Recent thymic emigrants and subsets of naive and memory T cells in the circulation of patients with head and neck cancer. Clin Immunol. 2005 Jul;116(1):27-36. doi: 10.1016/j.clim.2004.12.011. PubMed PMID: 15925829.
Wang J, Zhang X, Thomas SM, Grandis JR, Wells A, Chen ZG, Ferris RL. Chemokine receptor 7 activates phosphoinositide-3 kinase-mediated invasive and prosurvival pathways in head and neck cancer cells independent of EGFR. Oncogene. 2005 Sep 1;24(38):5897-904. doi: 10.1038/sj.onc.1208740. PubMed PMID: 16007209.
Ferris RL, Branstetter BF, Nayak JV. Diagnostic utility of positron emission tomography-computed tomography for predicting malignancy in cystic neck masses in adults. Laryngoscope. 2005 Nov;115(11):1979-82. doi: 10.1097/01.mlg.0000178328.70288.55. PubMed PMID: 16319609.
Albers AE, Ferris RL, Kim GG, Chikamatsu K, DeLeo AB, Whiteside TL. Immune responses to p53 in patients with cancer: enrichment in tetramer+ p53 peptide-specific T cells and regulatory T cells at tumor sites. Cancer Immunol Immunother. 2005 Nov;54(11):1072-81. doi: 10.1007/s00262-005-0670-9. Epub 2005 Jun 16. PubMed PMID: 15959774.
Kim JW, Ferris RL, Whiteside TL. Chemokine C receptor 7 expression and protection of circulating CD8+ T lymphocytes from apoptosis. Clin Cancer Res. 2005 Nov 1;11(21):7901-10. doi: 10.1158/1078-0432.CCR-05-1346. PubMed PMID: 16278415.
Albers A, Abe K, Hunt J, Wang J, Lopez-Albaitero A, Schaefer C, Gooding W, Whiteside TL, Ferrone S, DeLeo A, Ferris RL. Antitumor activity of human papillomavirus type 16 E7-specific T cells against virally infected squamous cell carcinoma of the head and neck. Cancer Res. 2005 Dec 1;65(23):11146-55. doi: 10.1158/0008-5472.CAN-05-0772. PubMed PMID: 16322265.
Mburu YK, Wang J, Wood MA, Walker WH, Ferris RL. CCR7 mediates inflammation-associated tumor progression. Immunol Res. 2006;36(1-3):61-72. doi: 10.1385/IR:36:1:61. Review. PubMed PMID: 17337767.
Rosenbloom AJ, Ferris RL, Sipe DM, Riddler SA, Connolly NC, Abe K, Whiteside TL. In vitro and in vivo protein sampling by combined microdialysis and ultrafiltration. J Immunol Methods. 2006 Feb 20;309(1-2):55-68. doi: 10.1016/j.jim.2005.11.013. Epub 2005 Dec 27. PubMed PMID: 16414066.
López-Albaitero A, Nayak JV, Ogino T, Machandia A, Gooding W, DeLeo AB, Ferrone S, Ferris RL. Role of antigen-processing machinery in the in vitro resistance of squamous cell carcinoma of the head and neck cells to recognition by CTL. J Immunol. 2006 Mar 15;176(6):3402-9. doi: 10.4049/jimmunol.176.6.3402. PubMed PMID: 16517708.
Albers AE, Visus C, Tsukishiro T, Ferris RL, Gooding W, Whiteside TL, De Leo AB. Alterations in the T-cell receptor variable beta gene-restricted profile of CD8+ T lymphocytes in the peripheral circulation of patients with squamous cell carcinoma of the head and neck. Clin Cancer Res. 2006 Apr 15;12(8):2394-403. doi: 10.1158/1078-0432.CCR-05-1818. PubMed PMID: 16638844.
Ferris RL, Whiteside TL, Ferrone S. Immune escape associated with functional defects in antigen-processing machinery in head and neck cancer. Clin Cancer Res. 2006 Jul 1;12(13):3890-5. doi: 10.1158/1078-0432.CCR-05-2750. Review. PubMed PMID: 16818683.
Andrade RS, Heron DE, Degirmenci B, Filho PA, Branstetter BF, Seethala RR, Ferris RL, Avril N. Posttreatment assessment of response using FDG-PET/CT for patients treated with definitive radiation therapy for head and neck cancers. Int J Radiat Oncol Biol Phys. 2006 Aug 1;65(5):1315-22. doi: 10.1016/j.ijrobp.2006.03.015. Epub 2006 Jun 5. PubMed PMID: 16750327.
Shurin MR, Shurin GV, Lokshin A, Yurkovetsky ZR, Gutkin DW, Chatta G, Zhong H, Han B, Ferris RL. Intratumoral cytokines/chemokines/growth factors and tumor infiltrating dendritic cells: friends or enemies?. Cancer Metastasis Rev. 2006 Sep;25(3):333-56. doi: 10.1007/s10555-006-9010-6. Review. PubMed PMID: 17029028.
Voynov G, Heron DE, Burton S, Grandis J, Quinn A, Ferris R, Ozhasoglu C, Vogel W, Johnson J. Frameless stereotactic radiosurgery for recurrent head and neck carcinoma. Technol Cancer Res Treat. 2006 Oct;5(5):529-35. doi: 10.1177/153303460600500510. PubMed PMID: 16981796.
Deleyiannis FW, Rogers C, Lee E, Russavage J, Gastman B, Dunklebarger J, Lai S, Ferris R, Myers EN, Johnson J. Reconstruction of the lateral mandibulectomy defect: management based on prognosis and location and volume of soft tissue resection. Laryngoscope. 2006 Nov;116(11):2071-80. doi: 10.1097/01.mlg.0000240858.88538.e1. PubMed PMID: 17075408.
Deleyiannis FW, Lee E, Gastman B, Nguyen D, Russavage J, Manders EK, Ferris RL, Myers EN, Johnson J. Prognosis as a determinant of free flap utilization for reconstruction of the lateral mandibular defect. Head Neck. 2006 Dec;28(12):1061-8. doi: 10.1002/hed.20463. PubMed PMID: 16823876.
Martinez I, Wang J, Hobson KF, Ferris RL, Khan SA. Identification of differentially expressed genes in HPV-positive and HPV-negative oropharyngeal squamous cell carcinomas. Eur J Cancer. 2007 Jan;43(2):415-32. doi: 10.1016/j.ejca.2006.09.001. Epub 2006 Oct 31. PubMed PMID: 17079134; PubMed Central PMCID: PMC1847595.
Linkov F, Lisovich A, Yurkovetsky Z, Marrangoni A, Velikokhatnaya L, Nolen B, Winans M, Bigbee W, Siegfried J, Lokshin A, Ferris RL. Early detection of head and neck cancer: development of a novel screening tool using multiplexed immunobead-based biomarker profiling. Cancer Epidemiol Biomarkers Prev. 2007 Jan;16(1):102-7. doi: 10.1158/1055-9965.EPI-06-0602. PubMed PMID: 17220337.
Lin CJ, Grandis JR, Carey TE, Gollin SM, Whiteside TL, Koch WM, Ferris RL, Lai SY. Head and neck squamous cell carcinoma cell lines: established models and rationale for selection. Head Neck. 2007 Feb;29(2):163-88. doi: 10.1002/hed.20478. Review. PubMed PMID: 17312569.
Ito D, Visus C, Hoffmann TK, Balz V, Bier H, Appella E, Whiteside TL, Ferris RL, DeLeo AB. Immunological characterization of missense mutations occurring within cytotoxic T cell-defined p53 epitopes in HLA-A*0201+ squamous cell carcinomas of the head and neck. Int J Cancer. 2007 Jun 15;120(12):2618-24. doi: 10.1002/ijc.22584. PubMed PMID: 17294448.
Agarwala SS, Cano E, Heron DE, Johnson J, Myers E, Sandulache V, Bahri S, Ferris R, Wang Y, Argiris A. Long-term outcomes with concurrent carboplatin, paclitaxel and radiation therapy for locally advanced, inoperable head and neck cancer. Ann Oncol. 2007 Jul;18(7):1224-9. doi: 10.1093/annonc/mdm088. PubMed PMID: 17675395.
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