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President-elect Donald Trump on Wednesday pledged to change the way the federal government purchases prescription drugs, a dramatic warning to the drug industry that he is serious about keeping his campaign promises to address drug costs.

He gave the subject near-top billing in his first press conference as president-elect, slamming the pharmaceutical industry for overseas production and promising, in vague terms, to open up more price negotiations for medications.

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“Our drug industry has been disastrous. They’re leaving left and right,” Trump said at the news conference at Trump Tower. “We have to get our drug industry coming back.”

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